Chemical burns of the eye occur mainly in the working-age population, and the development of various complications as a result of non-compliance with international standards in the provision of emergency medical care leads to disability.

Goals and objectives. Determination of the effectiveness of photodynamic therapy and complex treatment of chemical spectacle lenses using biochemical indicators of tears.

Materials and methods. In 2019 - 2022 110 patients (155 eyes) treated with GKBSMP with a diagnosis of chemical eye disease of I-II-III degree were divided into 3 groups: in the comparison group - patients who received standard therapy; the patient of the main group I additionally underwent PDT on the apparatus "Vostok"; in the II main group, methylethylpyridonol was added to the glass cap.

Quantitative biochemical method for the determination of superoxide dismutase (SOD), catalase (CT), malondialdehyde (MDA) and slezax.

Results and discussion. In treatments and all groups of treks, the amount of SOD and CT decreases by 1-2 times, and MDA increases by 3.5 times.

The activity of SOD below 7 was similar to that of PDT by 1.43 times, and in the treatment with methylated pyridinol - by 1.78 times, it was significantly higher than the comparison group and by 1.06 times. It was found that in patients of the main group II, activation of CT was 1.25 times, and the level of MDA was significantly reduced by 2.08 and 2.97 times compared with the values before treatment in both groups.

Conclusions. It has been proven that when using photodynamic therapy and complex treatment of chemical glasses, activation of the antioxidant system and increased epithelialization of damaged areas of the eye surface are more effective than with traditional treatment.

Chemical burn, photodynamic therapy, superoxidedismutase

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