The results of the assessment of ovarian reserve before and after the use of various methods of treatment based on ultrasound (counting the number of antral follicles) and biochemical methods showed that the levels of anti-Müllerian hormones and the number of antral follicles were lower in patients with bilateral ovarian disease, and were significantly lower in the group with combined treatment. Pregnancy occurred within a year after the end of treatment in 9 (12,7%) women of the first group and in 21 (22,6%) of the second group.

Capillary malformations (capillary angiodysplasia, CAD) in patients are an urgent problem of modern medicine due to functional, cosmetic, psychological disorders and social maladjustment of this category of patients in the absence of timely adequate treatment.

The article presents a retrospective analysis of the provision of medical care by otolaryngologists according to the data of a forensic medical examination. The analysis revealed the predominance of defects in diagnosis and treatment, which arose due to subjective reasons, more often in institutions of the prehospital and hospital stages, and in the outcome contributed to the onset of death or did not have a significant impact on the outcome.

In the algorithm of management of women with external genital endometriosis, it is advisable to include a study of the quality of life using the developed questionnaire "Health profile of patients with endometriosis", as well as the use of a visual analog scale (VAS) when assessing pain syndrome as a simple and objective criterion for assessing pain in clinical practice.

Modern educational technology in higher education is about problem-based learning, research and problem-solving. The purpose of problem-based learning is to find answers to educational problems, problems and questions in the process of working with students, to acquire new knowledge by solving them, to create and solve problem situations in the educational activities of students. With the help of problem-based learning, students develop a research approach to solving learning problems and specialization issues, the formation of independent learning skills.

Chemical burns of the eye occur mainly in the working-age population, and the development of various complications as a result of non-compliance with international standards in the provision of emergency medical care leads to disability.

Goals and objectives. Determination of the effectiveness of photodynamic therapy and complex treatment of chemical spectacle lenses using biochemical indicators of tears.

Materials and methods. In 2019 - 2022 110 patients (155 eyes) treated with GKBSMP with a diagnosis of chemical eye disease of I-II-III degree were divided into 3 groups: in the comparison group - patients who received standard therapy; the patient of the main group I additionally underwent PDT on the apparatus "Vostok"; in the II main group, methylethylpyridonol was added to the glass cap.

Quantitative biochemical method for the determination of superoxide dismutase (SOD), catalase (CT), malondialdehyde (MDA) and slezax.

Results and discussion. In treatments and all groups of treks, the amount of SOD and CT decreases by 1-2 times, and MDA increases by 3.5 times.

The activity of SOD below 7 was similar to that of PDT by 1.43 times, and in the treatment with methylated pyridinol - by 1.78 times, it was significantly higher than the comparison group and by 1.06 times. It was found that in patients of the main group II, activation of CT was 1.25 times, and the level of MDA was significantly reduced by 2.08 and 2.97 times compared with the values before treatment in both groups.

Conclusions. It has been proven that when using photodynamic therapy and complex treatment of chemical glasses, activation of the antioxidant system and increased epithelialization of damaged areas of the eye surface are more effective than with traditional treatment.

A new emergency method is proposed for determining the degree of microcirculation disorders in critical conditions in patients with acute cerebrovascular accident and severe traumatic brain injury, based on the capillary-venous difference in blood hemoglobin. The technical method is simple and convenient for any clinical laboratory and allows you to control the dynamics of the effectiveness of ongoing intensive care.