Articles
| Open Access |
https://doi.org/10.37547/ijmscr/Volume05Issue10-06
Analysis Of Epigenetic Changes In Cervical Dysplasia Associated With Human Papillomavirus (HPV)
Abstract
The aim of this review is to analyze the epigenetic mechanisms involved in the development of cervical intraepithelial neoplasia (CIN) associated with human papillomavirus (HPV) infection and to evaluate the prognostic potential of DNA methylation as a biomarker of precancerous cervical lesions. The review summarizes recent international studies (2010–2024) on DNA methylation of CADM1, MAL, FAM19A4, PAX1, and miR124-2 genes and their roles in epithelial transformation. The perspectives of implementing epigenetic testing in clinical screening and diagnosis of precancerous cervical conditions are also discussed.
Keywords
Cervical dysplasia, human papillomavirus, DNA methylation
References
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Copyright (c) 2025 Abdusattorova S., Alieva D.А.
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