Articles | Open Access | https://doi.org/10.37547/ijmscr/Volume05Issue09-05

Interaction Of Environmental And Dietary Factors In The Pathogenesis Of Cardiovascular Diseases

Farida Azizova , Doctor of Sciences (DSc), Associate Professor, Department of Functional Diagnostics, Center for the Professional Qualification Improvement of Medical Workers, Uzbekistan

Abstract

The article examines the relationship and interaction between environmental and dietary factors in the pathogenesis of cardiovascular diseases (CVD). Based on an analysis of current scientific sources, it emphasizes that environmental pollution (PM2.5, NO₂, heavy metals, organic toxins) and unhealthy dietary patterns (excess trans fats, salt, and antioxidant deficiency) exert a synergistic effect on the development of inflammatory and degenerative changes in the cardiovascular system. Particular attention is given to the mechanisms of interaction between these factors, which include oxidative stress, endothelial dysfunction, and mitochondrial disturbances. The article substantiates the need for a comprehensive preventive approach based on improving diet quality and reducing exposure to environmental risks.

Keywords

Cardiovascular diseases, nutrition, environmental factors, oxidative stress

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Farida Azizova. (2025). Interaction Of Environmental And Dietary Factors In The Pathogenesis Of Cardiovascular Diseases. International Journal of Medical Sciences And Clinical Research, 5(09), 29–34. https://doi.org/10.37547/ijmscr/Volume05Issue09-05