According to Charles Darwin’s first rule of regeneration, the higher the level of biological organization in a species, the lower its regenerative capacity. Regeneration is the biological process through which living organisms restore worn-out or damaged structures, often synonymously referred to as reparation. From a biological standpoint, regeneration is considered an adaptive mechanism. Virtually all diseases cause structural damage to tissues and organs, while recovery depends on the organism’s ability to regenerate these structures. This article explores the role of transforming growth factor beta 1 (TGF-β1) in tissue regeneration, highlighting its action through both dependent and independent signaling pathways.  

Regeneration, transforming growth factor beta 1 (TGF-β1), signaling pathways

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https://nveo.org/index.php/journal/article/view/3477/2855

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