The article examines incorporation as a word-formation and morphosyntactic mechanism reflecting national and cultural patterns of conceptualization in Russian and Uzbek. Based on a comparative analysis of culturally marked incorporating constructions, the study identifies differences in dominant referential domains, conceptual metaphors, and productive word-formation models. It is shown that in Russian incorporation is primarily oriented toward technical, professional, and terminological nomination, while its evaluative function is limited. In Uzbek, by contrast, incorporation is characterized by somatic, functional, and spatial conceptualization, demonstrating a somatocentric and culturally specific organization of linguistic experience.