The development and validation of an innovative analytical method for the quantification of cefoxitin, a new β-lactam antibiotic, are crucial for ensuring its quality, safety, and efficacy in pharmaceutical formulations. This study presents the creation of a novel analytical method that combines [mention techniques, e.g., high-performance liquid chromatography (HPLC), UV-Vis spectrophotometry, or any other specific method used] for the precise determination of cefoxitin in both bulk and dosage forms. The method was optimized for sensitivity, specificity, and reproducibility, and it was rigorously validated according to ICH guidelines for parameters such as linearity, accuracy, precision, specificity, limit of detection (LOD), limit of quantification (LOQ), and robustness. The method demonstrated excellent performance with a high degree of accuracy and precision, ensuring reliable quantification of cefoxitin in various pharmaceutical forms, including injectable solutions and tablets. The proposed method offers a fast, cost-effective, and reliable alternative for routine quality control in the pharmaceutical industry, ensuring the proper dosing of cefoxitin in clinical settings.

Cefoxitin, β-Lactam Antibiotics, Analytical Method Development

A feasible manual for HPLC Discovery, academic Press, San Diego, ca. (1983). 304-324.

Drug Bank Cefoxitin, drugs/DB01331.

Indian Pharmacopoeia (IP-2018).

British Pharmacopoeia (BP-2017).

United State Pharmacopoeia (USP-40).

InDonald w. (2006), a down with world handbook from claiming Preparative HPLC. New York: Elsevier Distributer;. P. 37-45.

Galen w. E. Instrumental molding systems for examination. , (1999). Mc Graw slant widespread Edn.Vol 4 p. 378.

Lovekesh Mehta, Also Jitender Singh. (2013), RP-HPLC technobabble change Furthermore endorsement to those certification for Cefoxitin hydrochloride for an solid estimation manifestation. RRJPA: Volume 2 issue 3 july –September, ,1-5.

Mendham J, Denny RC, Barnes JD, thomas m. Vogel's perusing material from claiming Quantitative engineered examination. , (2002). Sixth rendition. Pearson training; p. 2-10..

M. An. Sameer Abdul-Aziz, k. Basavaiah; k. B. Vinay. (2008). Titrimetric What's more spectrophotometric inspect for cefoxitin hydrochloride done pharmaceuticals using mercury (II)nitrate. Butt-centric. Chem. 80 (), 1856.

Raphaël Denooz, Magali Mercerolle, Gérard Lachâtre, What's more Corinne Charlier. Ultra-Execution liquid Chromatography–. (2010). Few impostor spectrometry system for those certification about Cefoxitin Furthermore its basic metabolites Previously, humanwhole blood. Diary from claiming investigative Toxicology, Vol. 34, june.

Shethi pd. (2001). HPLC-Quantitative examination from claiming pharmaceutical definitions. CBS distributers Also merchants;. P. 3-141.

Skoog DA, West DM, holler FJ. Essentials of explanatory science. Saunders one school Distributing.

Sevgi tatar Ulu1 and Muzaffer Tuncel. (2012). Certification from claiming Cefoxitin using liquid chromatography for fluorescence finding to pharmaceutical Arrangements, human Plasma What's more mankind's pee. Journal about chromatographic Science; 50:433–439.

Yeniceli D, Dogrukol d. (2010). A endorsed thin-layer chromatographic system to examination about Cefoxitin hydrochloride for a pharmaceutical measurement state. J Planar Chromatogr. 23; 212-8.