GENETIC RISK OF RESPIRATORY DISTRESS IN INFANTS
DOI:
https://doi.org/10.37547/ajbspi/Volume04Issue07-03Keywords:
Respiratory distress syndrome, genetic research, SFTPBAbstract
Respiratory distress syndrome (RDS) is one of the main causes of respiratory diseases and mortality among premature newborns. It requires intensive medical care, including mechanical ventilation and surfactant therapy. Timely detection and treatment of RDS are vital to prevent severe complications and improve outcomes in newborns. The study of genetic mutations, such as SFTPB, SFTPC, and ABCA3, which affect the production and function of surfactant, contributes to a deeper understanding of the pathophysiology of RDS and the development of targeted therapies. Treating newborns with RDS requires significant resources, including prolonged stays in neonatal intensive care units, increasing healthcare costs. Understanding genetic predisposition and individual risks for developing RDS allows for personalized approaches to treatment and prevention, improving the quality of medical care. Identifying risk factors such as cesarean section, multiple pregnancies, and maternal diseases helps develop preventive strategies to reduce RDS incidence. Research is ongoing to improve existing treatment methods and develop new therapeutic strategies, such as stem cell and gene therapy, to enhance outcomes in patients with RDS.
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