Skip to main content
editor@theusajournals.com | Oscar Publishing Services Journal Home
Login

International Journal of Medical Sciences And Clinical Research

Peer Reviewed | Open Access | E-ISSN: 2771-2265
Published Article

STUDY OF PSYCHOACTIVE ACTIVITY POTASSIUM SALT 5-(O-AMINOPHENYL)-1,3,4- OXADIAZOLE-2-THION (D-361)

STUDY OF PSYCHOACTIVE ACTIVITY POTASSIUM SALT 5-(O-AMINOPHENYL)-1,3,4- OXADIAZOLE-2-THION (D-361)

Authors

  • S.Z. Rashidov
    Junior scientific Researcher at the S.Y. Yunusov Institute of Plant Chemistry of the Academy of Sciences of the Republic of Uzbekistan
  • S.D. Rakhimboev
    Basic doctoral student of the Institute of Plant Chemistry named after S.Yu. Yunusov of the Academy of Sciences of the Republic of Uzbekistan
  • Z.I. Sanoev
    PhD, Senior scientific Researcher at the S.Yu. Yunusov Institute of Plant Chemistry of the Academy of Sciences of the Republic of Uzbekistan
  • I.T. Abdinazarov
    Basic doctoral student of the Institute of Plant Chemistry named after S.Yu. Yunusov of the Academy of Sciences of the Republic of Uzbekistan
  • T.T. Khamroev
    Basic doctoral student of the Institute of Plant Chemistry named after S.Yu. Yunusov of the Academy of Sciences of the Republic of Uzbekistan
  • D.S. Ismailova
    PhD, Senior scientific Researcher at the S.Yu. Yunusov Institute of Plant Chemistry of the Academy of Sciences of the Republic of Uzbekistan
  • B.J.Elmuradov
    Ds Doctor of Chemical Sciences, professor at the S.Yu. Yunusov Institute of Plant Chemistry of the Academy of Sciences of the Republic of Uzbekistan

DOI:

https://doi.org/10.37547/ijmscr/Volume02Issue09-01

Keywords:

Potassium salt 5-(o-aminophenyl)-1,3,4-oxadiazol-2-thione haloperidol psychostimulant

Abstract

These papers present a study of the synthetic compound potassium salt 5-(o-aminophenyl)-1,3,4-oxadiazol-2-thione (D-361) at doses of 10; 30 and 60 mg/kg by oral administration on motor activity, locomotor action of phenamine, haloperidol catalepsy and M-cholinergic receptors in experimental animals. Based on the results of the experiment, it was found that psychostimulating, partially dopamine-blocking, M-cholinergic blocking action.