This article examines postoperative anxiety and depression, focusing on the primary risk factors contributing to their development and the trajectories of psychological recovery following surgical interventions. The study is based on the analysis of contemporary scientific literature, as well as methods of synthesis, comparison, and generalization. Additionally, clinical observations and patient-reported outcomes are considered as supplementary sources. The analysis indicates that major risk factors include preoperative psychological status, severity of surgical trauma, postoperative pain, neuroendocrine stress response, inadequate social support, and prolonged hospitalization. The findings emphasize the importance of early psychological screening, multidisciplinary care, and structured rehabilitation programs to improve recovery outcomes and patient quality of life.
Postoperative Anxiety and Depression: Risk Factors and Recovery Trajectories
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Mavros M.N., et al. Postoperative psychological outcomes. Annals of Surgery. 2021.
Kiecolt-Glaser J.K. Stress and wound healing. Lancet. 2021.
Desborough J.P. Stress response to trauma and surgery. British Journal of Anaesthesia. 2022.
McEwen B.S. Neurobiology of stress. Physiological Reviews. 2021.
Black N. Patient-reported outcome measures. BMJ. 2022.
Hinrichs-Rocker A., et al. Preoperative anxiety. European Journal of Anaesthesiology. 2021.
Chrousos G.P. Stress and HPA axis. Endocrine Reviews. 2021.
Kehlet H., Dahl J.B. Multimodal analgesia. Anesthesia & Analgesia. 2021.
Glaser R., Kiecolt-Glaser J.K. Stress and immunity. Nature Reviews Immunology. 2022.
Dantzer R., et al. Inflammation and depression. Nature Reviews Neuroscience. 2021.
Besedovsky L., et al. Sleep and immune function. Pflügers Archiv. 2022.
Uchino B.N. Social support and health. Psychological Bulletin. 2021.
Rosenberger P.H., et al. Psychological recovery after surgery. Health Psychology. 2022.
Carver C.S., Connor-Smith J. Coping mechanisms. Annual Review of Psychology. 2022.
Phillips-Bute B., et al. Long-term outcomes after surgery. Anesthesiology. 2021.
Mitchell M. Psychological preparation. Journal of Advanced Nursing. 2022.
Engel G.L. Biopsychosocial model. Science.
Krishnan V., Nestler E.J. Neurobiology of depression. Nature. 2021.
Apfelbaum J.L., et al. Postoperative pain guidelines. Journal of Pain. 2022.
Hofmann S.G., et al. CBT for anxiety and depression. Psychiatric Clinics. 2021.
Alimirzayev, N. (2025, February). EFFECTS OF POSITIVE AND NEGATIVE EMOTIONS ON HUMAN HEALTH. In Международная конференция академических наук (Vol. 4, No. 2, pp. 39-42).
Abdivalievna, A. N. (2022). Psychocorrection of behavioral and emotional fields in children with attention deficit and hyperactive. British Journal of Global Ecology and Sustainable Development, 10, 132-137.
Askarova N.A. (2025). Psixopatik xususiyatli onalar munosabatining bola psixik taraqqiyotiga ta'siri. Inter Education & Global Study, (4).
Abdivalievna, A. N. (2023). Factors of Psychosomatic Diseases in School Children. European Journal of Pedagogical Initiatives and Educational Practices, 1(1), 65-67.
Abdivalievna, A. N. (2022). Psychological factors influencing the formation of anorexia nervous. British Journal of Global Ecology and Sustainable Development, 10, 152-155.
Factors of Psychosomatic Diseases in School Children. (2023). European Journal of Pedagogical Initiatives and Educational Practices, 1(1), 65-67.
Abdivaliyevna, A. N., & Jasurjon, R. (2025). O ‘qituvchi pedagogik faoliyatida kasbiy refleksiya o ‘rni va tarbiya jarayonidagi mahorati.