The article scientifically substantiates the possibility of adaptation of 16-17 year old adolescents to heavy physical activity and the compatibility of physiological processes with the mechanisms of action.

The article provides information that jobs and environmental pollution with various chemical dyes in many developed countries, including our country, have been proven to bring many pathological changes to the human body. This has been put into practice by many scholars. Under the insistence of a number of authors, the component of dyes used in dyeing-finishing workshops in textile enterprises is mainly organic compounds.

In hypertrophic cardiomyopathy, the walls of the ventricles of the heart continue with symmetric or asymmetric myocardial hypertrophy. Morphologically, in hypertrophic cardiomyopathy, fibrotic foci are detected based on the incorrect arrangement of myocardial muscle fibers, small coronary vessel syndrome, and myocardial hypertrophy.

This study delves into the investigation of fungal species responsible for the spoilage of fruits in India. Through isolation and characterization techniques, diverse fungal strains were identified from spoiled fruit samples collected across different regions. Morphological, biochemical, and molecular analyses were employed to elucidate the taxonomy and traits of the isolated fungi. The findings shed light on the diversity and prevalence of fungal culprits contributing to fruit spoilage in the Indian context, providing insights crucial for effective management and preservation strategies in the fruit industry.

Reducing perinatal morbidity and mortality is one of the main tasks of the maternal and child health care system. Congenital anomalies contribute significantly to these indicators and occupy leading positions in terms of prevalence. According to the World Health Organization, 25% of newborns are born with developmental defects. In light of this data, increasing the efficiency of early medical care and reducing growth and development-related disorders in newborns is crucial. Congenital anomalies of the digestive tract occupy a primary place, corresponding to 21.7%-25%. Currently, perinatal studies of the problem of mother and child with congenital digestive tract anomalies are considered separately, which is significant for perinatal diagnostics, the ability to predict congenital digestive tract anomalies, and determining tactics. This is of great importance for both pediatricians and surgeons. As a first step in creating a system for assessing and improving medical services provided to the younger generation, it is important to optimize medical care for newborns with surgical diseases.

The choice of this particular topic is due to the need to study morphofunctional studies and compare them with radiological data. The literature shows that in order to improve and timely diagnosis and prevention of inflammatory diseases of the bronchopulmonary system, the director carries out radiological diagnostic methods. Morphological studies of pleural fluid can affect the diagnosis and treatment of children with pneumonia.

The article describes recommendations for correcting water-electrolyte balance during physical training of football players, as well as daily energy expenditure and caloric content of daily menu products.

Effects of alcohol metabolites, mainly acetaldehyde, on the heart. Disturbances in metabolism and electrolyte imbalance lead to arrhythmias and disturbances in the functional activity of the heart. Acetaldehyde disrupts the synthesis of several compounds and increases the synthesis of inflammatory cytokines and leads to the development of an autoimmune process. The weight of the heart is 500-550 gr. and it is observed that it is filled with fat. When the heart is placed on the operating table, it is diffuse, similar to infectious myocarditis, and the heart is red or purple in color.

This article provides a comprehensive overview of clinical pharmacology, highlighting its historical development, significance, key roles, and notable achievements. It explains how clinical pharmacology has evolved from its origins in the early 20th century to a crucial discipline in modern medicine. The article elucidates the roles of clinical pharmacologists in drug development and approval, optimizing therapeutic regimens, regulatory and policy development, education and training, and clinical research and innovations. It also outlines significant achievements, such as the advent of precision medicine, improvements in drug safety and pharmacovigilance, advancements in chronic disease management, and enhanced therapeutic outcomes. Finally, the article looks ahead to future directions in the field, emphasizing the potential impact of digital health, artificial intelligence, pharmacogenomics, and biotechnology.

Studying the morphological and genetic different types of keratoses is key for correct diagnosis and choice of treatment. The association between metabolic disorders and skin diseases highlights the need for an integrated approach to the management of patients with chronic diseases, including diabetes mellitus. Further research is needed to better understand the pathogenesis and develop effective treatments.

This article discusses the practical significance of the saffron plant. Information was also given about the saffron plant, its systematic place, practical significance and diseases, which were approved in antiquity.