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American Journal of Applied Science and Technology

Peer Reviewed | Open Access | E-ISSN: 2771-2745
Published Article

Angiogenesis In Acute Coronary Syndrome: Mechanisms And The Role Of Biomarkers

Angiogenesis In Acute Coronary Syndrome: Mechanisms And The Role Of Biomarkers

Authors

  • Shukurov I.B.
    Candidate of Biological Sciences, Professor at Bukhara State Medical Institute, Uzbekistan

DOI:

https://doi.org/10.37547/ajast/Volume05Issue10-06

Keywords:

Angiogenesis Acute coronary syndrome Hypoxia Hypoxia-inducible factor (HIF-1α)

Abstract

The aim of the study was to identify the relationship between biomarkers of hypoxia, inflammation, and endothelial dysfunction in patients with acute coronary syndrome. The study included 62 male patients aged 24 to 50 years who were hospitalized for ACS.

Key markers associated with angiogenesis and hypoxia were studied: hypoxia-inducible factor-1 (HIF-1), vascular endothelial growth factor (VEGF), endothelin-1, von Willebrand factor, and xanthine oxidase activity. These biomarkers reflect the molecular mechanisms of angiogenesis and endothelial dysfunction.

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