The relevance of this study is determined by the rapid transition of higher education institutions to distance and blended learning formats, which necessitates a reconsideration of traditional pedagogical methods. Didactic games function as an effective tool for activating students’ cognitive activity, maintaining motivation, and developing key competencies, especially under conditions of remote interaction. The article analyzes the opportunities and limitations of using didactic games in distance learning within the university context. Based on theoretical analysis, pedagogical practice, and empirical data, the advantages and challenges of implementing game-based pedagogies in online environments are examined, and the conditions for their successful integration into the educational process are identified. Recommendations for instructors and instructional designers on optimizing the use of didactic games in distance learning are proposed.