In patients with acute coronary syndrome, a significant increase in the levels of the studied biomarkers was detected: hypoxia-induced factor-1 — 2.1 times, vascular endothelial growth factor (VEGF) — 1.8 times, endothelin-1 — 5.8 times, xanthine oxidase activity — 48%.
The data obtained indicate pronounced endothelial dysfunction and activation of angiogenic processes, which is of important prognostic and clinical significance in the management of patients with ACS.
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