Objective: to evaluate the clinical effectiveness of a developed step-by-step algorithm for diagnosis and management of pregnant women with cervical pathology. Materials and methods: 120 pregnant women with cervical pathology were included. The main group (n=60) was managed according to the new algorithm; the comparison group (n=60) received standard care. Results: Disease stabilization without dysplasia progression was recorded in 93.3% of the main group vs 81.7% in the comparison group at 6 months. The diagnostic significance of HPV was confirmed: χ²=4.60 (p=0.032), RR=1.79, Se=64.1%, Sp=56.8%. Conclusion: The optimized step-by-step algorithm significantly improves clinical outcomes compared to standard management (93.3% vs 81.7%).
Effectiveness of An Optimized Diagnostic and Management Algorithm for Pregnant Women with Cervical Pathology
DOI:
Keywords:
Cervical pathology
pregnancy
diagnostic algorithm
Abstract
References
Ruzieva NH. Preclinical diagnosis of preterm birth. Medical News. 2019;7(298):74–75.
Ruzieva NH, Shodieva HT, Nazarova DE. Pregnancy course, delivery, and perinatal outcomes in patients with urinary tract infections. In: Science of the XXI Century: Theory, Practice and Prospects. 2015:266.
Ruzieva NH, Nazarova DE. Changes in genital microflora in women of reproductive age. In: International Scientific and Practical Conference Proceedings. 2016:218–222.
Ziyaeva ER, Ruzieva NH, Sobirova MR. Chronic pelvic pain syndrome in chronic salpingo-oophoritis: a modern view on pathogenesis. Re-health Journal. 2022;2(14):1–5.
Ruzieva N. Characteristics of some predictors of miscarriage. Doctor’s Herald. 2019;1(2):89–92.
Djabbarova LA, Kuldoshov A, Ruzieva N. Genital tuberculosis as a cause of female infertility. Prospects for the Development of Medicine. 2021;1(1):65–66.
Ruzieva NH, Shodieva HT, Nazarova DE. Pregnancy course, delivery, and perinatal outcomes in patients with urinary tract infections. In: Science of the XXI Century: Theory, Practice and Prospects. 2015:266–268.
Nigina KI, Janna PY. Assessment of intestinal and vaginal microbiome during in vitro fertilization programs. Systematic Reviews in Pharmacy. 2020;11(11).
Djabbarova LA, Ruzieva NH. Use of international approaches to determine causes and ways to reduce preterm birth rates. In: VolgaMedScience Proceedings. 2021:304–305.
Ruzieva NH. The role of oxidative stress in the development of preterm birth. Tashkent: Ministry of Health of the Republic of Uzbekistan; 2019:40.
Ruzieva NH, Juraeva NA. Cervical pathology in pregnant women with HPV, vaginal flora disturbances, and without HPV. Innovative Research in the Modern World: Theory and Practice. 2024;3(11):161–162.
Ikhtiyarova GA, Dustova NK, Bakhramova SU, Ruzieva NH, Irgashev DS, Matrizaeva GD. Molecular genetic markers of hypertension risk in pregnant women with antiphospholipid syndrome. Clinical Review in General Medicine. 2024;5(9):62–69.
Ruzieva N, Sunnatillaeva S, Abulkosimova D. The impact of adhesions formed after pelvic surgery on girls. Science and Technology in the Modern World. 2023;2(16):12–13.
Ruzieva N, Sunnatillaeva S, Abulkosimova D. The impact of adhesions after pelvic surgery on girls. Bulletin of Teachers of New Uzbekistan. 2023;1(5 Part 2):123–126.
Ruzieva NH, Pakhomova JE. Cytokine study results in pregnant women at risk of preterm birth. In: Modern Perinatal Medical Technologies in Solving Demographic Safety Problems. 2023:196.
Ruzieva NH, Kayumova DT, Turbanova UV. Pregnancy course, delivery outcomes, and placental condition in women after SARS-CoV-2 (COVID-19): clinical and morphological parallels. Moscow; 2022.
Rozhkova E, Ruzieva N, Ergashev Z. Improvement of methodologies for protection of structures from thermal effects. In: E3S Web of Conferences. 2021;264:02033.
Ruzieva NH, Pakhomova JE. Original articles. Doctor’s Herald. 2023;7.
Ruzieva NH, Djabbarova LA, Djabbarova YK. Causes and ways to reduce preterm birth using international approaches. Re-health Journal. 2021;1(9):14–18.
Nazarova DE, Ruzieva NK, Turbanova UV, Rassadina MV. The role of oxidative stress in the development of premature childbirth. Central Asian Journal of Pediatrics. 2021;(1):30–36.
Yuldashev AY, Yuldasheva SZ, Ruzieva NH. Formation of digestive, absorptive, and immune systems in the small intestine mucosa during early postnatal ontogenesis. Tashkent; 2017:132.
Ruzieva N, Sunnatillaeva S, Ahmadalieva M. The impact of adhesions after pelvic surgery on girls. Central Asian Journal of Education and Innovation. 2023;2(3 Part 2):79–82.