This study delves into the complex relationship between bacterial types and antibiotic resistance and their influence on clinical outcomes in pediatric sepsis patients at Sanglah Hospital, Bali-Indonesia. Sepsis, a life-threatening condition, requires timely and effective antibiotic treatment. However, the rise of antibiotic resistance poses a significant challenge. Through a comprehensive analysis of clinical data and bacterial isolates, this research investigates the impact of different bacterial types and their antibiotic resistance profiles on patient outcomes. The study aims to provide insights into optimizing sepsis management strategies, improving patient care, and addressing the growing concern of antibiotic resistance.