The target of this exploration was to set up a gastroretentive medication conveyance arrangement of Ranitidine hydrochloride. Speedy GI travel could bring about fragmented medication discharge from the medication conveyance framework over the assimilation zone prompting diminished viability of the controlled portion and in this way less quiet consistence. Drifting framework tablets containing 150 mg Ranitidine were created involving distinctive bubbly salts and polymer in blends.