This review systematizes current knowledge about umbilical cord abnormalities (UCAs) — a heterogeneous group of anomalies including length abnormalities, number of vessels, attachments, nodes, cysts, and vascular malformations. Based on the analysis of scientific literature (2000–2024), the epidemiological data are presented: UCAs occur in 15–35% of pregnancies, with single umbilical artery (SUA) — in 0.5–5%, velmen insertion — up to 50% in monochorionic twins, and true nodes — in 0.3–1.2%. The review details complications: fetal growth restriction (FGR), chronic and acute hypoxia, antenatal death, risks during childbirth (vascular rupture in vasa praevia, asphyxia). Particular attention is paid to early diagnostic methods: ultrasound with Doppler (blood flow assessment, EAP), color Doppler mapping (Velmen attachment), 3D/4D ultrasound in STIC mode (nodes, spatial anomalies), CTG monitoring. Differentiated management tactics are substantiated: from dynamic observation at low risk to planned cesarean section for vasa praevia or IUGR. It is emphasized that timely diagnostics and an individualized approach reduce perinatal mortality and improve outcomes.

Umbilical cord cysts, varicose umbilical veins (varix), Pregnancy complications

Hasegawa J, et al. Umbilical cord diameter in the second trimester and pregnancy outcome. J Perinat Med. 2016;44(7):777-782. doi:10.1515/jpm-2015-0269.

Sepulveda W, et al. Prenatal diagnosis and outcome of umbilical vein varix. Ultrasound Obstet Gynecol. 2018;52(6):807-812. doi:10.1002/uog.19000.

Khalil A, et al. Association between first-trimester umbilical cord diameter and pregnancy complications. Prenat Diagn. 2019;39(11):998-1004. doi:10.1002/pd.5529.

Perez-Cosio C, et al. Thin umbilical cord: a retrospective cohort study. J Matern Fetal Neonatal Med. 2021;34(20):3309-3314. doi:10.1080/14767058.2019.1683549.

Sinkovskaya E, et al. Umbilical vein varix: prenatal diagnosis and management. J Ultrasound Med. 2019;38(8):2179-2185. doi:10.1002/jum.14911.

Ghi T, et al. Prognostic value of Doppler assessment in fetuses with umbilical vein varix: a multicenter study. Ultrasound Obstet Gynecol. 2020;55(2):227-233. doi:10.1002/uog.20397.

Prefumo F, et al. The natural history of umbilical cord cysts: a role for three-dimensional ultrasound? Prenat Diagn. 2016;36(13):1196-1200. doi:10.1002/pd.4961

Zhou Y, et al. Clinical characteristics and outcomes of prenatally diagnosed true umbilical cord cysts: a single-center experience. J Matern Fetal Neonatal Med. 2022;35(25):6484-6489. doi:10.1080/14767058.2021.1914578.

WHO. ICD-10: International Statistical Classification of Diseases and Related Health Problems, 10th Revision. 2019.

WHO. ICD-11: International Classification of Diseases, 11th Revision. 2023. https://icd.who.int/en

American Institute of Ultrasound in Medicine (AIUM). Practice Parameter for the Performance of Detailed Diagnostic Obstetric Ultrasound Examinations Between 12 Weeks 0 Days and 13 Weeks 6 Days. 2020.

Society for Maternal-Fetal Medicine (SMFM). Electronic address: pubs@smfm.org. #46: Diagnosis and management of vasa previa. Am J Obstet Gynecol. 2020;223(3):B2-B14. doi:10.1016/j.ajog.2020.05.019.

Furuya M, et al. Rupture of an umbilical vein varix during labor: a case report and literature review. J Med Case Rep. 2018;12(1):195. doi:10.1186/s13256-018-1739-3.

Raio L, et al. The clinical significance of prenatally diagnosed true umbilical cord cysts: a systematic review. Prenat Diagn. 2017;37(8):735-742. doi:10.1002/pd.5087.

Iskandarovna T. N. REVIEW OF THE LITERATURE ON RECENT RESEARCH IN THE FIELD OF OBSTETRICS AND GYNECOLOGY //International Journal of Medical Sciences And Clinical Research. – 2024. – Т. 4. – №. 12. – С. 28-33.

Iskandarovna T. N. CURRENT TRENDS IN GYNECOLOGY //International Journal of Medical Sciences And Clinical Research. – 2024. – Т. 4. – №. 05. – С. 91-96.

Zafarovna B. Z. SEXUAL DYSFUNCTION IN PREGNANCY: PROBLEMS AND SOLUTIONS //International Journal of Medical Sciences And Clinical Research. – 2024. – Т. 4. – №. 10. – С. 30-34.