Peritoneal Dialysis and Uremic Tumoral Calcinosis: A Case Report of an Atypical Presentation and Review of the Literature

Dr. Clara J. Muller — Tue, 01 Apr 2025 00:00:00 +0000

Background: Uremic tumoral calcinosis (UTC) is a rare complication associated with chronic kidney disease (CKD) and is commonly observed in patients with end-stage renal disease (ESRD) on dialysis, particularly hemodialysis. UTC is characterized by the deposition of calcium phosphate in soft tissues, most notably around joints, and is typically seen in patients with hyperphosphatemia, hyperparathyroidism, and elevated calcium-phosphate product. However, atypical manifestations of UTC, particularly in patients on peritoneal dialysis (PD), are seldom reported.

Case Presentation: We report the case of a 62-year-old male with a history of ESRD on peritoneal dialysis who developed an unusual presentation of uremic tumoral calcinosis. The patient presented with an enlarging mass in the left shoulder, which was initially misdiagnosed as a soft tissue infection. Radiological and histopathological examination confirmed the diagnosis of UTC. The patient was managed with phosphate binders, adjustments to his dialysis regimen, and surgical debridement.

Conclusion: This case highlights the importance of considering uremic tumoral calcinosis in the differential diagnosis of soft tissue masses in ESRD patients, even those on peritoneal dialysis. Early diagnosis and management are essential in preventing severe complications. We review the current literature on UTC in dialysis patients, emphasizing the need for vigilant monitoring and individualized treatment plans.

International Journal of Medical Sciences And Clinical Research

Peritoneal Dialysis and Uremic Tumoral Calcinosis: A Case Report of an Atypical Presentation and Review of the Literature